Rat Bile Sampling, Blood Sampling, and Infusion

Use this system for short-term bile collection where replacement salts are not required and where two vascular catheters are placed, one for intermittent manual blood sampling and the other for continuous drug infusion from a syringe pump — four catheters in total.

During surgery, connect the bile duct catheter to the blue port of an implanted four-channel Vascular Access Button™, the duodenal catheter to the white port, and the venous and arterial catheter to the green and red ports. Prime then install the VABR4L to connect the blue and white ports so that bile can flow in an extracorporeal loop while the animal recovers from surgery, leaving the arterial and venous catheters locked.

To collect bile, infuse drugs and sample blood simultaneously, connect a four-channel VAB™ tether that:

• connects the blue port to a primed line through a two-channel swivel to a collection vial at animal level (so that bile can flow at its natural rate without fighting gravity)
• leaves the white duodenal port unconnected
• connects the venous (green port) catheter to an infusion pump through the swivel
• connects the arterial catheter (red port) to a PinPort™ at the top of the tether where blood samples can be collected manually without touching the animal.

With imagination, many other configurations are possible.  For more information please complete this form to define your ideal configuration and contact us to discuss your needs before ordering.